Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.42 |
| ▸ | HRH2 | P25021 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11209515 | 0.97 | BCHE (0.42) | HRH4HRH2BCHEACHE | |
| SCHEMBL9870811 | 0.89 | ACHE (0.41) | BCHEACHE | |
| SCHEMBL9870816 | 0.89 | ACHE (0.41) | BCHEACHE | |
| SCHEMBL9870818 | 0.86 | HRH4 (0.44) | HRH4 | |
| SCHEMBL11371367 | 0.83 | ACHE (0.69) | BCHEACHE | |
| SCHEMBL11244766 | 0.83 | ACHE (0.40) | BCHEACHE | |
| SCHEMBL11209512 | 0.81 | CYP2D6 (0.40) | BCHEACHE | |
| SCHEMBL11290548 | 0.80 | ACHE (0.42) | BCHEACHE | |
| SCHEMBL11290545 | 0.80 | ACHE (0.42) | BCHEACHE | |
| SCHEMBL11374134 | 0.80 | CYP2D6 (0.40) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366164-A | HISTAMINE H2-ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 1982-12-28 | — | — | US | disclosed |
| US-4317819-A | Amine derivatives | GLAXO GROUP LIMITED (GB) | 1982-03-02 | — | — | US | disclosed |
| US-4264614-A | HISTAMINE ANTAGONIST; ANTIALLERGENS; ANTISECRETORY AND ANTIINFLAMMATORY AGENTS | GLAXO GROUP LIMITED (GB) | 1981-04-28 | — | — | US | disclosed |