Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.42 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290548 | 1.00 | ACHE (0.42) | ACHEBCHEKMT2AKDM4EALDH1A1 | |
| SCHEMBL9870811 | 0.83 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL9870816 | 0.83 | ACHE (0.41) | ACHEBCHE | |
| SCHEMBL11209515 | 0.81 | BCHE (0.42) | ACHEBCHE | |
| SCHEMBL11244775 | 0.80 | HRH4 (0.42) | ACHEBCHE | |
| SCHEMBL9593812 | 0.80 | FAAH (0.49) | — | |
| SCHEMBL9593815 | 0.80 | FAAH (0.49) | — | |
| SCHEMBL11290549 | 0.79 | ACHE (0.42) | ACHEBCHE | |
| SCHEMBL9593379 | 0.77 | FAAH (0.49) | — | |
| SCHEMBL9593372 | 0.77 | FAAH (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057564-A1 | Process for preparing 3,5-diamino-1,2,4-triazoles | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-11 | — | — | EP | claimed |
| EP-0057564-A1 | Process for preparing 3,5-diamino-1,2,4-triazoles | SMITHKLINE BECKMAN CORPORATION (US) | 1982-08-11 | — | — | EP | disclosed |