Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.62 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.62 |
| ▸ | S1PR2 | O95136 | 11/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.49 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.47 |
| ▸ | FDPS | P14324 | 4/20 | 0.47 |
| ▸ | LAP3 | P28838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29263967 | 1.00 | LPAR3 (0.62) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL11439929 | 0.92 | LPAR3 (0.50) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL22291102 | 0.89 | LPAR3 (0.67) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL665561 | 0.89 | FDPS (0.56) | LPAR3LPAR2FDPSLAP3 | |
| SCHEMBL27288350 | 0.87 | FDPS (0.57) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL2775267 | 0.87 | LPAR3 (0.63) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL865495 | 0.87 | FDPS (0.54) | LPAR3LPAR2FDPSLAP3 | |
| SCHEMBL2701703 | 0.87 | FDPS (0.54) | LPAR3LPAR2FDPSLAP3 | |
| SCHEMBL21385015 | 0.87 | FDPS (0.54) | FDPSLAP3 | |
| SCHEMBL20565552 | 0.87 | FDPS (0.54) | LPAR3LPAR2FDPSLAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0013491-B1 | DISPERSIONS OF SILICEOUS SOLIDS IN LIQUID ORGANIC MEDIA | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-10-20 | — | — | EP | disclosed |