Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.67 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.67 |
| ▸ | S1PR2 | O95136 | 11/20 | 0.56 |
| ▸ | S1PR1 | P21453 | 11/20 | 0.56 |
| ▸ | S1PR3 | Q99500 | 11/20 | 0.56 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.56 |
| ▸ | FDPS | P14324 | 4/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28235584 | 0.92 | FDPS (0.63) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL24462564 | 0.92 | FDPS (0.63) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL28236747 | 0.92 | FDPS (0.63) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL22895133 | 0.92 | FDPS (0.63) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL31169460 | 0.90 | FDPS (0.61) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL11406656 | 0.90 | LPAR3 (0.75) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL11244820 | 0.89 | LPAR3 (0.62) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL29263967 | 0.89 | LPAR3 (0.62) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL6012146 | 0.88 | LPAR3 (0.71) | LPAR3LPAR2S1PR2S1PR1S1PR3 | |
| SCHEMBL22605995 | 0.87 | LPAR3 (0.69) | LPAR3LPAR2S1PR2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917499-A1 | ADHESIVE/ADSORPTION SWITCH ON NANOPARTICLES TO INCREASE TUMOR UPTAKE AND DELAY TUMOR CLEARANCE | The Johns Hopkins University (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2020160147-A1 | ADHESIVE/ADSORPTION SWITCH ON NANOPARTICLES TO INCREASE TUMOR UPTAKE AND DELAY TUMOR CLEARANCE | THE JOHNS HOPKINS UNIVERSITY (US) | 2020-08-06 | — | — | WO | disclosed |