Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 5/20 | 0.80 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11240834 | 0.92 | PTGES (0.90) | PTGESPTGS2TP53MAPTMGAM | |
| SCHEMBL11477119 | 0.89 | PTGES (1.00) | PTGESPTGS2TP53MAPT | |
| SCHEMBL11231108 | 0.88 | PTGES (0.71) | PTGESPTGS2TP53MAPTMGAM | |
| SCHEMBL11475990 | 0.87 | PTGES (0.62) | PTGESPTGS2TP53MAPTGAA | |
| SCHEMBL11483239 | 0.86 | PTGES (0.61) | PTGESPTGS2TP53MAPTGAA | |
| SCHEMBL11467233 | 0.82 | PTGES (0.71) | PTGESPTGS2TP53MAPTMGAM | |
| SCHEMBL11240864 | 0.80 | NPSR1 (0.64) | PTGESPTGS2TP53MAPTLMNA | |
| SCHEMBL11485804 | 0.79 | PTGES (0.53) | PTGESPTGS2TP53MAPTLMNA | |
| SCHEMBL11485871 | 0.79 | PTGES (0.53) | PTGESPTGS2TP53GAALMNA | |
| SCHEMBL11476538 | 0.79 | TP53 (0.62) | PTGESPTGS2TP53MAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318911-A | 5,6-Diaryl-1,2,4-triazines as topical antithrombotic agents | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |