Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4592225 | 0.93 | EPHX2 (0.51) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL7926 | 0.91 | EPHX2 (0.49) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL28539557 | 0.89 | EPHX2 (0.48) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL9349123 | 0.86 | EPHX2 (0.47) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL7791787 | 0.84 | PADI1 (0.46) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL28991011 | 0.84 | HDAC8 (0.45) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL28991008 | 0.84 | HDAC8 (0.45) | HDAC8HDAC6EPHX2MEN1KMT2A | |
| SCHEMBL13779902 | 0.82 | EPHX2 (0.50) | EPHX2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL14084928 | 0.82 | EPHX2 (0.47) | EPHX2MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL9186695 | 0.81 | EPHX2 (0.47) | HDAC8HDAC6EPHX2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348401-A | ANTIHISTAMINIC, ANTIEDEMIC, ANTIPHLOGISTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1982-09-07 | — | — | US | disclosed |