⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5394254 | 0.90 | HSD11B1 (0.47) | — | |
| SCHEMBL17077671 | 0.89 | HSD11B1 (0.33) | — | |
| SCHEMBL18355602 | 0.89 | HSD11B1 (0.33) | — | |
| SCHEMBL4461573 | 0.85 | SIGMAR1 (0.39) | — | |
| SCHEMBL4129790 | 0.84 | HSD11B1 (0.33) | — | |
| SCHEMBL8517450 | 0.80 | HSD11B1 (0.38) | — | |
| SCHEMBL5389801 | 0.77 | CRBN (0.37) | — | |
| SCHEMBL18356163 | 0.76 | HSD11B1 (0.35) | — | |
| SCHEMBL8074588 | 0.76 | HSD11B1 (0.35) | — | |
| SCHEMBL24306403 | 0.70 | HSD11B1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309436-A | 3'(3,5-Dichlorophenyl)-spiro(3-oxabicycloc[3.1.0]hexane)-6,5'-oxazolidine-2',4'-dione | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |