SCHEMBL11244837

SCHEMBL11244837

Cc1ccccc1Cc1ccc(OP(O)Oc2ccccc2C(C)(C)C)c(Cc2ccccc2C)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
FFAR4 Q5NUL3 2/20 0.34
NR3C1 P04150 1/20 0.34
FFAR1 O14842 1/20 0.34
ALDH1A1 P00352 4/20 0.33
KDM4E B2RXH2 3/20 0.33
GAA P10253 2/20 0.33
MAPT P10636 3/20 0.32
NAMPT P43490 1/20 0.32
TP53 P04637 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
IDO1 P14902 1/20 0.31
HSPA5 P11021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11263755 0.90 ALDH1A1 (0.37) RXRARXRBRXRGNR3C1ALDH1A1
SCHEMBL11253348 0.83 CNR1 (0.34) RXRARXRBRXRGFFAR4FFAR1
SCHEMBL11249529 0.82 PPARG (0.32) FFAR4FFAR1MAPTTP53MEN1
SCHEMBL11261905 0.81 APEX1 (0.33) NR3C1ALDH1A1KDM4EMAPTHSPA5
SCHEMBL11268364 0.79 CNR2 (0.38) KDM4ECNR2
SCHEMBL11252511 0.76 CYP2D6 (0.35) FFAR1ALDH1A1KDM4EMEN1LMNA
SCHEMBL11261959 0.76 MRGPRX4 (0.33) NR3C1KDM4ETP53CNR2
SCHEMBL11254545 0.76 ALDH1A1 (0.45) RXRARXRBRXRGALDH1A1KDM4E
SCHEMBL11256601 0.73 ESR1 (0.31) GABRA1GABRB2CNR2TDP1
SCHEMBL27889522 0.71 APEX1 (0.41) RXRARXRBRXRGALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4346025-A Stabilized vinyl chloride polymer comprising a phenylethylidene aryl phosphite ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-08-24 US disclosed