Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARD | Q03181 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.30 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244837 | 0.82 | RXRA (0.36) | TP53FFAR4FFAR1MEN1LMNA | |
| SCHEMBL11261905 | 0.81 | APEX1 (0.33) | MAPT | |
| SCHEMBL11249531 | 0.80 | GAA (0.33) | TP53FFAR4FFAR1USP2KMT2A | |
| SCHEMBL11263755 | 0.75 | ALDH1A1 (0.37) | TP53MAPT | |
| SCHEMBL11253348 | 0.74 | CNR1 (0.34) | PPARGPPARAFFAR4FFAR1LMNA | |
| SCHEMBL11262011 | 0.73 | ALDH1A1 (0.41) | TP53USP2MEN1LMNAPOLB | |
| SCHEMBL11252511 | 0.69 | CYP2D6 (0.35) | FFAR1MEN1LMNAPOLBKMT2A | |
| SCHEMBL11261959 | 0.69 | MRGPRX4 (0.33) | TP53 | |
| SCHEMBL11268364 | 0.69 | CNR2 (0.38) | — | |
| SCHEMBL15377372 | 0.68 | USP2 (0.39) | TP53USP2MEN1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4346025-A | Stabilized vinyl chloride polymer comprising a phenylethylidene aryl phosphite | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |