Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.33 |
| ▸ | NOS3 | P29474 | 3/20 | 0.33 |
| ▸ | NOS2 | P35228 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469451 | 0.64 | NOS1 (0.40) | NOS1NOS3NOS2 | |
| SCHEMBL14132252 | 0.63 | NOS1 (0.37) | NOS1NOS3NOS2 | |
| SCHEMBL9006300 | 0.62 | NOS1 (0.31) | NOS1NOS3NOS2 | |
| SCHEMBL5542352 | 0.61 | S100A4 (0.33) | NOS1NOS3NOS2 | |
| SCHEMBL17321809 | 0.60 | IDO1 (0.40) | — | |
| SCHEMBL3885169 | 0.59 | TSHR (0.37) | — | |
| SCHEMBL17286959 | 0.58 | NOS1 (0.41) | NOS1NOS3NOS2 | |
| SCHEMBL13945520 | 0.58 | NOS1 (0.37) | NOS1NOS3NOS2 | |
| SCHEMBL12352022 | 0.58 | NOS1 (0.37) | NOS1NOS3NOS2 | |
| SCHEMBL27425408 | 0.57 | IDO1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4366312-A | Metal complexes of isoindolinazines, process for their preparation and use | CIBA-GEIGY CORPORATION (US) | 1982-12-28 | — | — | US | disclosed |