Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244987 | 0.81 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL7978087 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL11748737 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL31096462 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL28711958 | 0.79 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL1942660 | 0.77 | ALDH1A1 (0.53) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL3825769 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL3081344 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL13684907 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B | |
| SCHEMBL12805341 | 0.75 | ALDH1A1 (0.54) | ALDH1A1KDM4EHTR1AADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348401-A | ANTIHISTAMINIC, ANTIEDEMIC, ANTIPHLOGISTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1982-09-07 | — | — | US | disclosed |