Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244866 | 0.81 | ALDH1A1 (0.49) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL973234 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| Hydrochloric Acid SCHEMBL13857771 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL1444254 | 0.78 | CYP1A2 (0.55) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL10356325 | 0.77 | ALDH1A1 (0.56) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL11748737 | 0.76 | ALDH1A1 (0.54) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL30283197 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL5451 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1HTR1AADRA2AADRA2BMAOA | |
| SCHEMBL15541094 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ADRA2AHTR2BNPC1RAB9A | |
| SCHEMBL6958088 | 0.76 | ALDH1A1 (0.58) | ALDH1A1ADRA2AHTR2BNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4348401-A | ANTIHISTAMINIC, ANTIEDEMIC, ANTIPHLOGISTIC | BOEHRINGER MANNHEIM GMBH (DE) | 1982-09-07 | — | — | US | disclosed |