Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6261613 | 0.90 | FAAH (0.58) | FAAHTSHRSLC22A6ALDH1A1SMN1; SMN2 | |
| SCHEMBL2418248 | 0.87 | — | — | |
| SCHEMBL13378646 | 0.86 | FAAH (0.50) | FAAHTSHRALDH1A1LMNAMAPT | |
| SCHEMBL11254676 | 0.85 | TSHR (0.47) | FAAHTSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1304773 | 0.84 | — | — | |
| SCHEMBL11141201 | 0.82 | FAAH (0.52) | FAAHTSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL9724633 | 0.82 | LMNA (0.61) | FAAHTSHRSLC22A6ALDH1A1LMNA | |
| SCHEMBL1115668 | 0.82 | — | — | |
| SCHEMBL28519995 | 0.82 | FAAH (0.52) | FAAHTSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11722823 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0026846-B1 | SUBSTITUTED FULVALENOPHANE DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF Aktiengesellschaft (DE) | 1982-06-23 | — | — | EP | disclosed |
| US-4298751-A | Cyclically substituted fulvalenophanes | BASF AKTIENGESELLSCHAFT (DE) | 1981-11-03 | — | — | US | disclosed |
| EP-0026846-A1 | Substituted fulvalenophane derivatives, their preparation and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |