Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10784208 | 0.82 | KDR (0.40) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL11245157 | 0.76 | KDR (0.39) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL7841843 | 0.74 | NPC1 (0.47) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL10783775 | 0.74 | KDM4E (0.42) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL10787265 | 0.72 | KDM4E (0.43) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 | |
| SCHEMBL432645 | 0.65 | LMNA (0.70) | ALDH1A1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL15611296 | 0.65 | POLB (0.41) | ALDH1A1POLBSMN1; SMN2HPGDKDM4E | |
| SCHEMBL5659407 | 0.65 | SMN1; SMN2 (0.55) | ALDH1A1SMN1; SMN2L3MBTL1MAPK1KDM4E | |
| SCHEMBL11618490 | 0.63 | MAPT (0.50) | ALDH1A1L3MBTL1NPSR1PTGDR2MAPT | |
| SCHEMBL23660618 | 0.62 | MAPT (0.51) | ALDH1A1POLBSMN1; SMN2L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060094-A2 | Guanidine derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-15 | — | — | EP | disclosed |