Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864966 | 0.95 | LMNA (0.67) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL431027 | 0.95 | LMNA (0.67) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL433166 | 0.92 | LMNA (0.74) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14385817 | 0.82 | LMNA (1.00) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL432515 | 0.82 | ALDH1A1 (0.57) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29120323 | 0.81 | ALDH1A1 (0.54) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL434346 | 0.81 | ALDH1A1 (0.57) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL18805587 | 0.81 | LMNA (0.62) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20545187 | 0.81 | ALDH1A1 (0.56) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL431034 | 0.80 | ALDH1A1 (0.56) | LMNAALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103003242-B | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2015-04-22 | — | — | CN | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| EP-2595957-B1 | PYRIDIN-2-YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2014-08-13 | — | — | EP | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| US-8680288-B2 | Pyridin-2yl sulfanyl acid esters and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-25 | — | — | US | disclosed |
| EP-2595957-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | Council of Scientific & Industrial Research (IN) | 2013-05-29 | — | — | EP | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-05-23 | — | — | US | disclosed |
| CN-103003242-A | Pyridin-2-ylsulfanyl esters and methods of making the same | COUNCIL SCIENT IND RES | 2013-03-27 | — | — | CN | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012011123-A1 | PYRIDIN- 2 - YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131350-A1 | PYRIDIN-2YL SULFANYL ACID ESTERS AND PROCESS FOR THE PREPARATION THEREOF | VCAM1, ICAM1, CCL5 | LMNA 1729/4885ALDH1A1 634/4885SMN1; SMN2 2409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.