Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 8/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 8/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.30 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.30 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.30 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245207 | 0.91 | AKR1C2 (0.35) | AKR1C2AKR1C1NR1H4 | |
| SCHEMBL11245202 | 0.87 | AKR1C2 (0.55) | AKR1C2AKR1C1AKR1C4AKR1C3EIF4A3 | |
| SCHEMBL11228742 | 0.75 | AKR1C2 (0.58) | AKR1C2AKR1C1AKR1C4AKR1C3EIF4A3 | |
| SCHEMBL9247751 | 0.75 | AKR1C2 (0.67) | AKR1C2AKR1C1AKR1C4AKR1C3CYP2C19 | |
| SCHEMBL29193192 | 0.69 | NR5A2 (0.43) | AKR1C2AKR1C1CYP2C19CYP2C9PPARG | |
| SCHEMBL11776441 | 0.64 | CYP2D6 (0.50) | AKR1C2AKR1C1AKR1C4AKR1C3CYP2C19 | |
| SCHEMBL11246149 | 0.64 | AKR1C2 (0.44) | AKR1C2AKR1C1CYP2C19CYP2C9MCL1 | |
| SCHEMBL28717119 | 0.64 | AKR1C2 (0.53) | AKR1C2AKR1C1AKR1C4AKR1C3RXRA | |
| SCHEMBL10136530 | 0.64 | RXRA (0.47) | EIF4A3CYP2D6CYP2C9HIF1ARXRA | |
| SCHEMBL13896481 | 0.63 | TPMT (0.46) | AKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4355070-A | COLOR FORMER, DEVELOPER, HEAT FUSIBLE MATERIAL AND OIL ABSORPTIVE PIGMENT | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1982-10-19 | — | — | US | disclosed |
| US-4236732-A | COLOR DEVELOPING LAYER CONTAINING PARTICLES OF A CHROMOGENIC MATERIAL, AN ACCEPTOR AND A HEAT FUSIBLE MATERIAL | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1980-12-02 | — | — | US | disclosed |
| US-4228222-A | COLOR DEVELOPING LAYER INCLUDING WATER SOLUBLE RESIN AS BINDER | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1980-10-14 | — | — | US | disclosed |