Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | MEN1 | O00255 | 2/20 | 0.72 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.72 |
| ▸ | PTGES | O14684 | 11/20 | 0.69 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11258989 | 0.84 | KMT2A (1.00) | KMT2AMEN1NLRP3PTGS2POLB | |
| SCHEMBL22259732 | 0.82 | PTGES (0.63) | KMT2AMEN1NLRP3PTGESALDH1A1 | |
| SCHEMBL22260230 | 0.82 | PTGES (1.00) | KMT2APTGESKDM4EHPGDNPSR1 | |
| SCHEMBL22260247 | 0.82 | PTGES (0.73) | KMT2AMEN1PTGESALDH1A1KDM4E | |
| SCHEMBL22259985 | 0.81 | PTGES (0.80) | KMT2AMEN1NLRP3PTGESPTGS2 | |
| SCHEMBL27440613 | 0.81 | PTGES (0.65) | KMT2AMEN1NLRP3PTGESALDH1A1 | |
| SCHEMBL22260235 | 0.81 | PTGES (1.00) | KMT2APTGESKDM4EHPGDNPSR1 | |
| SCHEMBL27440624 | 0.81 | PTGES (0.68) | KMT2AMEN1NLRP3PTGESALDH1A1 | |
| SCHEMBL28358360 | 0.80 | PTGS2 (0.94) | KMT2AMEN1NLRP3PTGS2POLB | |
| SCHEMBL3447906 | 0.80 | PTGS2 (1.00) | KMT2AMEN1NLRP3PTGS2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |