SCHEMBL11245307

SCHEMBL11245307

CNN1C(=O)c2cc(O)c3ccccc3c2C1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.39
ESR1 P03372 2/20 0.38
ESR2 Q92731 2/20 0.38
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA9 Q16790 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 3/20 0.36
ALDH1A1 P00352 3/20 0.36
HTT P42858 2/20 0.36
LMNA P02545 1/20 0.36
KDM4E B2RXH2 4/20 0.36
MCL1 Q07820 2/20 0.36
NSD2 O96028 1/20 0.36
POLB P06746 1/20 0.36
PTGS1 P23219 1/20 0.36
PTGS2 P35354 1/20 0.36
BCL2 P10415 1/20 0.34
TRPM4 Q8TD43 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11711956 0.84 PTGS1 (0.40) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL11256719 0.82 CYP1A2 (0.56) ESR1ESR2CA12CA1CA9
SCHEMBL11715759 0.81 CYP1A2 (0.47) MEN1KMT2AMAPTALDH1A1HTT
SCHEMBL11713596 0.81 PTGS1 (0.42) CA12CA1CA9MEN1KMT2A
SCHEMBL9006282 0.79 CA12 (0.43) ESR1ESR2CA12CA1CA9
SCHEMBL11251045 0.79 MAPT (0.46) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL11712187 0.76 KMT2A (0.44) CA12CA1CA9MEN1KMT2A
SCHEMBL10969739 0.76 ALDH1A1 (0.38) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL15680564 0.75 BCL2 (0.37) ESR1ESR2MEN1KMT2AMAPT
SCHEMBL9006350 0.75 KDM4E (0.49) MEN1KMT2AMAPTALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023666-B1 ANTHRAQUINONE-AZOMETHINE COMPOUNDS, PROCESS FOR THEIR PREPARATION AS WELL AS A PROCESS FOR PIGMENTING ORGANIC MACROMOLECULAR MATERIALS BAYER AG (DE) 1982-10-13 EP disclosed
US-4323670-A Anthraquinone-azomethine compounds, processes for their preparation and processes for pigmenting organic macromolecular substances BAYER AKTIENGESELLSCHAFT (DE) 1982-04-06 US disclosed
EP-0023666-A1 Anthraquinone-azomethine compounds, process for their preparation as well as a process for pigmenting organic macromolecular materials BAYER AG (DE) 1981-02-11 EP disclosed