Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11711956 | 0.83 | PTGS1 (0.40) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL11712187 | 0.81 | KMT2A (0.44) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL11245307 | 0.81 | IDO1 (0.39) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL11714586 | 0.79 | KMT2A (0.48) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL11256719 | 0.78 | CYP1A2 (0.56) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL11251045 | 0.75 | MAPT (0.46) | PTGS2ALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL11715759 | 0.75 | CYP1A2 (0.47) | PTGS1PTGS2ALDH1A1MAPTRAB9A | |
| SCHEMBL11713604 | 0.72 | KMT2A (0.51) | PTGS1PTGS2ALDH1A1MAPTKDM4E | |
| SCHEMBL9006282 | 0.72 | CA12 (0.43) | ALDH1A1MAPTKDM4ELMNAMEN1 | |
| SCHEMBL10969739 | 0.70 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4ERAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055565-A | Optical brightening agents of naphthalimide derivatives | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-10-25 | — | — | US | disclosed |