Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | GLA | P06280 | 1/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.73 |
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6431712 | 0.90 | KDM4E (0.59) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL14451818 | 0.86 | KDM4E (0.73) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL30309460 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL354881 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL3410798 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL31321876 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL9036025 | 0.79 | KDM4E (1.00) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL5760847 | 0.79 | KDM4E (0.73) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL9500995 | 0.79 | ALDH1A1 (0.73) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL29690461 | 0.78 | TXNRD1 (0.42) | KDM4EALDH1A1HPGDGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | UNIV UTAH RES FOUND (US) | 2017-01-05 | — | — | US | disclosed |
| US-4322414-A | MITICIDES; APHIDICIDES; LARVICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170001970-A1 | Substituted benzohydrazide analogs as histone demethylase inhibitors | KDM1B, KDM2A, KDM1A | KDM4E 23/4885ALDH1A1 1174/4885HPGD 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.