Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259488 | 0.92 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL11854549 | 0.84 | MAOA (0.45) | CYP1A2CYP2C9ALDH1A1CYP3A4CA2 | |
| SCHEMBL11849338 | 0.79 | CYP1A2 (0.47) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL11250494 | 0.77 | ALDH1A1 (0.46) | CYP1A2CYP2C9ALDH1A1TSHRLMNA | |
| SCHEMBL11849121 | 0.77 | ALDH1A1 (0.36) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL39353 | 0.77 | CYP2C9 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL8854338 | 0.77 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL30008257 | 0.77 | CYP1A2 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL29357192 | 0.77 | CYP2C9 (0.61) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR | |
| SCHEMBL9413678 | 0.75 | CYP2C9 (0.59) | CYP1A2CYP2C9CYP2C19ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31002-E | N-(3-Hydroxyaryl-propyl)-imides | CIBA-GEIGY CORPORATION (US) | 1982-07-27 | — | — | US | disclosed |
| US-4066616-A | ORGANIC POLYMERS | CIBA-GEIGY CORPORATION (US) | 1978-01-03 | — | — | US | disclosed |
| US-3992420-A | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3956298-A | POLYMER STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |