Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.43 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245411 | 1.00 | AKR1B1 (0.51) | AKR1B1ALPGTTRP4HBP2RX3 | |
| SCHEMBL11255538 | 0.90 | ALPG (0.44) | AKR1B1ALPGTTRP2RX3 | |
| SCHEMBL11255541 | 0.90 | ALPG (0.44) | AKR1B1ALPGTTRP2RX3 | |
| SCHEMBL11243598 | 0.89 | ALPG (0.43) | AKR1B1ALPGTTR | |
| SCHEMBL11243612 | 0.89 | ALPG (0.43) | AKR1B1ALPGTTR | |
| SCHEMBL11254681 | 0.89 | P2RX3 (0.46) | AKR1B1ALPGP2RX3 | |
| SCHEMBL11254686 | 0.89 | P2RX3 (0.46) | AKR1B1ALPGP2RX3 | |
| SCHEMBL11243822 | 0.89 | ALPG (0.56) | AKR1B1ALPG | |
| SCHEMBL11243817 | 0.89 | ALPG (0.56) | AKR1B1ALPG | |
| SCHEMBL11248463 | 0.86 | AKR1B1 (0.52) | AKR1B1ALPGTTRP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4341780-A | Substituted pyrido [1,2-a] pyrimidines useful as anti-allergic, anti-ulcer and anti-diabetic agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-07-27 | — | — | US | disclosed |
| US-4310526-A | Substituted 6,7-methylene pyrido[1,2-a]pyrimidines useful as anti-allergic and anti-ulcer agents | FARMITALIA CARLO ERBA S.P.A. (IT) | 1982-01-12 | — | — | US | disclosed |