Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250063 | 1.00 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11253078 | 1.00 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11247900 | 1.00 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11246892 | 1.00 | GPR35 (0.72) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL2295037 | 0.99 | GPR35 (0.70) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11248651 | 0.99 | GPR35 (0.74) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11142080 | 0.96 | GPR35 (0.74) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL11244502 | 0.94 | GPR35 (0.76) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL9847173 | 0.94 | GPR35 (0.65) | GPR35LMNATDP1MEN1KMT2A | |
| SCHEMBL9847108 | 0.94 | GPR35 (0.65) | GPR35LMNATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4362742-A | TOPICAL APPLICATION | SULLIVAN THOMAS J | 1982-12-07 | — | — | US | disclosed |
| US-4271182-A | TOPICAL APPLICATION OF 1,3-BIS((2-CARBOXY-CHROMON-5-)OXY)-2-HYDROXYPROPANE | FISONS LIMITED (GB) | 1981-06-02 | — | — | US | disclosed |