Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 5/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11077750 | 0.92 | CYP19A1 (0.42) | CYP19A1KIF11MEN1KMT2ALMNA | |
| SCHEMBL11492725 | 0.85 | CYP1A2 (0.48) | CYP19A1CYP2C9CYP1A2KIF11MEN1 | |
| SCHEMBL7734271 | 0.85 | CYP2C9 (0.48) | PTPN1CYP2C9KIF11 | |
| SCHEMBL7729779 | 0.83 | CYP2C9 (0.50) | CYP2C9CYP1A2KIF11ALOX5TAAR1 | |
| SCHEMBL11286839 | 0.82 | CYP19A1 (0.37) | CYP19A1PTPN1CYP2C9CYP1A2KIF11 | |
| SCHEMBL11256138 | 0.82 | CYP19A1 (0.40) | CYP19A1PTPN1CYP2C9CYP1A2KIF11 | |
| SCHEMBL28428044 | 0.80 | CYP3A4 (0.44) | CYP19A1CYP1A2KIF11MEN1KMT2A | |
| SCHEMBL11574355 | 0.78 | CYP19A1 (0.49) | CYP19A1KIF11LMNAKDM4E | |
| SCHEMBL11481112 | 0.76 | CYP2A6 (0.52) | — | |
| SCHEMBL362964 | 0.76 | TSHR (0.43) | PTPN1CYP2C9CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322442-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1982-03-30 | — | — | US | disclosed |