SCHEMBL362964

SCHEMBL362964

C#CC(O)(c1ccccc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
ALDH1A1 P00352 5/20 0.41
CYP1A2 P05177 2/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
KDM4E B2RXH2 1/20 0.38
PABPC1 P11940 1/20 0.38
APOBEC3A P31941 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
KCNN4 O15554 2/20 0.38
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.36
ATM Q13315 1/20 0.36
ALOX15 P16050 1/20 0.36
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
PTPN1 P18031 1/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL8511811 0.91 KCNN4 (0.43) TSHRALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL7734271 0.89 CYP2C9 (0.48) TSHRALDH1A1CYP2C9PTPN1
Alcohol SCHEMBL7269785 0.89 ALDH1A1 (0.45) TSHRALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL26629595 0.89 ESR1 (0.52) TSHRALDH1A1KMT2AMEN1ESR1
SCHEMBL4796677 0.87 MEN1 (0.44) TSHRALDH1A1KMT2AMEN1ESR1
SCHEMBL30056216 0.87 LMNA (0.41) TSHRALDH1A1ATMALOX15ESR1
SCHEMBL3217833 0.87 KCNN4 (0.47) ALDH1A1CYP2C9CYP2C19KCNN4KMT2A
SCHEMBL28428044 0.87 CYP3A4 (0.44) TSHRCYP1A2KCNN4KMT2AMEN1
SCHEMBL7032980 0.87 ALDH1A1 (0.56) TSHRALDH1A1PTPN1CYP3A4
SCHEMBL11259996 0.87 AHR (0.40) ALDH1A1CYP1A2CYP2C9CYP2C19KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559655-B2 Polysiloxane-containing temporary adhesive comprising heat-resistant polymerization inhibitor NISSAN CHEMICAL CORPORATION (JP) 2026-02-24 US claimed
CN-119432316-A Organic silicon pressure-sensitive adhesive and preparation method and application thereof 成都拓利科技股份有限公司 2025-02-14 CN claimed
CN-118812988-B Light aging resistant bamboo powder bio-based degradation material for agricultural mulching film and preparation method thereof 汕头市雷氏塑化科技有限公司 2025-02-07 CN claimed
CN-118812988-A Light aging resistant bamboo powder bio-based degradation material for agricultural mulching film and preparation method thereof 汕头市雷氏塑化科技有限公司 2024-10-22 CN claimed
CN-112574421-B Modified MQ resin and preparation method and application thereof 万华化学集团股份有限公司 2022-09-16 CN claimed
US-20210130666-A1 POLYSILOXANE-CONTAINING TEMPORARY ADHESIVE COMPRISING HEAT-RESISTANT POLYMERIZATION INHIBITOR NISSAN CHEMICAL CORPORATION (JP) 2021-05-06 US claimed
CN-112574421-A Modified MQ resin and preparation method and application thereof 万华化学集团股份有限公司 2021-03-30 CN claimed
EP-3790038-A1 TEMPORARY ADHESIVE CONTAINING POLYSILOXANE THAT CONTAINS HEAT RESISTANT POLYMERIZATION INHIBITOR Nissan Chemical Corporation (JP) 2021-03-10 EP claimed
CN-112074931-A Temporary adhesive containing polysiloxane containing heat-resistant polymerization inhibitor 日产化学株式会社 2020-12-11 CN claimed
EP-3245256-A1 ORGANOPOLYSILOXANE PREPOLYMER AND CURABLE ORGANOPOLYSILOXANE COMPOSITION COMPRISING SAME Henkel AG & Co. KGaA (DE) 2017-11-22 EP claimed
US-7727692-B2 Electrophotographic photoreceptor, image forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2010-06-01 US claimed
WO-2010037550-A1 METHOD FOR PREPARATION OF RUTHENIUM-INDENYLIDENE CARBENE CATALYSTS UMICORE AG & CO. KG (DE) 2010-04-08 WO claimed
US-7109377-B2 Synthesis of combinatorial libraries of compounds reminiscent of natural products PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-09-19 US claimed
EP-1615931-A1 TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME Biogen Idec MA Inc. (US) 2006-01-18 EP claimed
WO-2004092177-A1 TRIAZOLOPYRAZINES AND METHODS OF MAKING AND USING THE SAME BIOGEN IDEC MA INC. (US) 2004-10-28 WO claimed
US-20030082830-A1 Synthesis of combinatorial libraries of compounds reminiscent of natural products NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2003-05-01 US claimed
EP-0622420-B1 Long chain alpha-acetylenic alcohols as inhibitors for hydrosilylation reactions, their use for preparing stable curable silicone compositions RHODIA CHIMIE SA (FR) 2002-10-02 EP claimed
US-6448443-B1 GENERATED FROM DIVERSIFIABLE SCAFFOLDS SYNTHESIZED FROM THE PYRIDINE-BASED TEMPLATE ISONICOTINAMIDE; ALSO PROVIDES A NOVEL ORTHO-NITROBENZYL PHOTOLINKER; SYNTHESIZED FROM A SHIKIMIC ACID BASED EPOXYOL TEMPLATE PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-09-10 US claimed
WO-2000006525-A9 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS HARVARD COLLEGE (US) 2000-04-20 WO claimed
WO-2000006525-A2 SYNTHESIS OF COMBINATORIAL LIBRARIES OF COMPOUNDS REMINISCENT OF NATURAL PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2000-02-10 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559655-B2 Polysiloxane-containing temporary adhesive comprising heat-resistant polymerization inhibitor ITGA1, HSPA1A, TCP1 TSHR 1618/4885ALDH1A1 445/4885CYP1A2 2704/4885
US-20030082830-A1 Synthesis of combinatorial libraries of compounds reminiscent of natural products TKFC, NISCH, PTGIS TSHR 4277/4885ALDH1A1 568/4885CYP1A2 312/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.