Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 2/20 | 0.37 |
| ▸ | FNTB | P49356 | 2/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11128323 | 0.81 | KMT2A (0.45) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11271369 | 0.81 | MEN1 (0.52) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11251274 | 0.81 | KMT2A (0.44) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL11252020 | 0.79 | KMT2A (0.42) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL6681598 | 0.78 | ANPEP (0.42) | KMT2AMEN1NPC1RAB9AFNTA | |
| SCHEMBL27768608 | 0.78 | ANPEP (0.42) | KMT2AMEN1NPC1RAB9AFNTA | |
| SCHEMBL11252386 | 0.78 | KMT2A (0.49) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL9081277 | 0.77 | NPC1 (0.42) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL2328144 | 0.76 | MEN1 (0.45) | KMT2AMEN1ALDH1A1LMNAPOLB | |
| SCHEMBL9082541 | 0.75 | LMNA (0.43) | KMT2AMEN1ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066956-A1 | Enkephalinase enzyme inhibiting compounds | PFIZER INC. (US) | 1982-12-15 | — | — | EP | disclosed |
| US-4329495-A | USEFUL AS ANALGESICS OR ANTICONVULSANTS, CHIRAL 2-(2-BENZYL-3-MERCAPTOPROPIONYLAMINO)-THIOBUTYRIC ACIDS, OR ALKANOL DERIVATIVES | PFIZER INC. (US) | 1982-05-11 | — | — | US | disclosed |