SCHEMBL27768608

SCHEMBL27768608

CSCCC(C(=O)O)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.42
LTA4H P09960 1/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
GAA P10253 1/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
CHRNB2 P17787 1/20 0.40
CHRNB4 P30926 1/20 0.40
CHRNA3 P32297 1/20 0.40
CHRNA4 P43681 1/20 0.40
RNPEP Q9H4A4 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6681598 1.00 ANPEP (0.42) ANPEPLTA4HMEN1KMT2ANPC1
SCHEMBL9082541 0.93 LMNA (0.43) ANPEPLTA4HMEN1KMT2ANPC1
SCHEMBL9081277 0.86 NPC1 (0.42) ANPEPLTA4HMEN1KMT2ANPC1
SCHEMBL840672 0.82 LMNA (0.46) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL841385 0.82 LMNA (0.46) MEN1KMT2ANPC1RAB9ACA12
SCHEMBL536546 0.79 CPA3 (0.53) NPC1RAB9A
SCHEMBL19384899 0.79 CPA3 (0.53) NPC1RAB9A
SCHEMBL536547 0.79 CPA3 (0.53) NPC1RAB9A
SCHEMBL538188 0.79 ANPEP (0.38) ANPEPLTA4HGAAFNTAFNTB
SCHEMBL11245665 0.78 KMT2A (0.46) ANPEPMEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105452288-A Anti-human papillomavirus 16E 6T cell receptor US HEALTH (US) 2016-03-30 CN disclosed
CN-104968675-A T cell receptor recognizing MHC class II restricted MAGE-A3 US HEALTH (US) 2015-10-07 CN disclosed
CN-103124740-B Anti-SSX-2T cell receptor and associated materials and using method THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2015-09-02 CN disclosed
CN-104822705-A M971 chimeric antigen receptor US HEALTH (US) 2015-08-05 CN disclosed
CN-104507963-A Murine anti-NY-ESO-1T cell receptors US HEALTH (US) 2015-04-08 CN disclosed
CN-102746378-B Anti-fatty acid synthetase polypeptide and its application Bio tech ltd, Tianjin Top Tyke (CN) 2014-10-22 CN disclosed
CN-103992388-A Anti-hepatitis B virus X protein peptide medicament TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2014-08-20 CN disclosed
CN-103974974-A T-cell receptors recognizing HLA-A1-or HLA-CW 7-restricted MAGE US HEALTH (US) 2014-08-06 CN disclosed
CN-103748107-A Pseudomonas exotoxin a with less immunogenic t cell and/or b cell epitopes US HEALTH (US) 2014-04-23 CN disclosed
CN-103596981-A Anti-epidermal growth factor receptor variant III chimeric antigen receptors and their use for treating cancer US HEALTH (US) 2014-02-19 CN disclosed
CN-102675422-B Anti-hepatitis B virus X protein polypeptide medicine TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2014-02-05 CN disclosed
CN-102675423-B Polypeptide medicine against hepatitis B virus X protein TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2014-02-05 CN disclosed
CN-103435694-A Smoothened polypeptides and methods of use US GOV HEALTH & HUMAN SERV (US) 2013-12-11 CN disclosed
CN-101616931-B Smoothened polypeptides and methods of use US GOV HEALTH & HUMAN SERV (US) 2013-08-21 CN disclosed
CN-103124740-A Anti-SSX-2 T cell receptors and related materials and methods of use US HEALTH (US) 2013-05-29 CN disclosed
CN-102746378-A Anti-fatty acid synthetase polypeptide and its application TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2012-10-24 CN disclosed
CN-102675422-A Anti-hepatitis B virus X protein polypeptide medicine TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-102675424-A Polypeptide drug for resisting Hepatitis B virus X protein TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-102675423-A Polypeptide medicine against hepatitis B virus X protein TIANJIN TOPTECH BIO SCIENCE & TECHNOLOGY CO LTD 2012-09-19 CN disclosed
CN-101616931-A SMOOTHENED polypeptides and methods of use US GOV HEALTH & HUMAN SERV (US) 2009-12-30 CN disclosed