Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1567424 | 0.84 | DDB1 (0.67) | DDB1CRBNCYP19A1SIRT2ALDH1A1 | |
| SCHEMBL8300066 | 0.84 | DDB1 (0.67) | DDB1CRBNCYP19A1SIRT2ALDH1A1 | |
| Methane SCHEMBL7953352 | 0.82 | DDB1 (0.65) | DDB1CRBNCYP19A1SIRT2ALDH1A1 | |
| SCHEMBL4971631 | 0.77 | DDB1 (0.49) | DDB1CRBNCYP19A1SIRT2ALDH1A1 | |
| Carbamic Acid SCHEMBL28839963 | 0.77 | CYP19A1 (0.62) | DDB1CRBNCYP19A1SIRT2ALDH1A1 | |
| SCHEMBL12698414 | 0.74 | ALDH1A1 (0.58) | DDB1CRBNSIRT2ALDH1A1TSHR | |
| SCHEMBL7156373 | 0.74 | ALDH1A1 (0.58) | DDB1CRBNSIRT2ALDH1A1TSHR | |
| SCHEMBL880376 | 0.74 | ALDH1A1 (0.58) | DDB1CRBNSIRT2ALDH1A1TSHR | |
| SCHEMBL5386997 | 0.71 | MAPT (0.59) | DDB1CRBNALDH1A1TSHRHSD17B10 | |
| SCHEMBL4263409 | 0.70 | LMNA (0.47) | DDB1CRBNCYP19A1SIRT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106922129-B | Methods of conjugating polypeptides | 免疫医疗有限责任公司 | 2024-02-20 | — | — | CN | disclosed |
| EP-3200829-B1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE LLC (US) | 2023-12-06 | — | — | EP | disclosed |
| US-20220160882-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | MEDIMMUNE, LLC | 2022-05-26 | — | — | US | disclosed |
| EP-0005348-B1 | CARBAPENEM DERIVATIVES, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| US-4278686-A | ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1981-07-14 | — | — | US | disclosed |
| EP-0005348-A1 | Carbapenem derivatives, a process for their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1979-11-14 | — | — | EP | disclosed |
| EP-0005349-A1 | Alkylcarbapenems, their preparation, use in pharmaceutical compositions and intermediates | BEECHAM GROUP PLC (GB) | 1979-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160882-A1 | METHOD OF CONJUGATING A POLYPEPTIDE | ZYX, QPCT, MRPL21 | DDB1 2719/4885CRBN 1083/4885CYP19A1 1622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.