Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10661301 | 0.86 | ADRB2 (0.57) | ADRB2ADRB1DRD2PGRSLC6A4 | |
| SCHEMBL11253640 | 0.85 | ADRB2 (0.52) | ADRB2ADRB1ADRB3DRD2PGR | |
| SCHEMBL11369783 | 0.84 | ADRB2 (0.51) | ADRB2ADRB1ADRB3DRD2PGR | |
| Salmefamol SCHEMBL20285629 | 0.83 | ADRB2 (0.67) | ADRB2ADRB1ADRB3DRD2PGR | |
| Salmefamol SCHEMBL30361710 | 0.83 | ADRB2 (0.67) | ADRB2ADRB1ADRB3DRD2PGR | |
| Salmefamol SCHEMBL18458 | 0.83 | ADRB2 (0.67) | ADRB2ADRB1ADRB3DRD2PGR | |
| SCHEMBL11174404 | 0.81 | ADRB2 (0.61) | ADRB2ADRB1ADRB3SLC6A4ADRA1A | |
| SCHEMBL9664001 | 0.81 | ADRB2 (0.63) | ADRB2ADRB1ADRB3DRD2PGR | |
| SCHEMBL10661718 | 0.81 | ADRB2 (0.63) | ADRB2ADRB1ADRB3DRD2PGR | |
| SCHEMBL10662533 | 0.81 | ADRB2 (0.63) | ADRB2ADRB1ADRB3DRD2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4338333-A | ANTIOBESITY, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1982-07-06 | — | — | US | claimed |
| US-4338333-A | ANTIOBESITY, HYPOGLYCEMIC | BEECHAM GROUP LIMITED (GB) | 1982-07-06 | — | — | US | disclosed |