Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11245718 | 0.84 | ADRB2 (0.54) | ADRB2ADRB1ADRB3ADRA1ADRD2 | |
| SCHEMBL11369787 | 0.84 | ADRB2 (0.52) | ADRB2ADRB1ADRB3CYP1A2CYP2D6 | |
| SCHEMBL11249876 | 0.84 | ADRB2 (0.69) | ADRB2ADRB1ADRB3GLAADRA1A | |
| SCHEMBL10661301 | 0.84 | ADRB2 (0.57) | ADRB2ADRB1ADRA1ADRD2CYP1A2 | |
| SCHEMBL11253640 | 0.83 | ADRB2 (0.52) | ADRB2ADRB1ADRB3ADRA1ADRD2 | |
| Acetic Acid SCHEMBL5286403 | 0.81 | ADRB2 (0.61) | ADRB2ADRB1ADRB3SLC2A1ADRA1A | |
| Acetic Acid SCHEMBL5388441 | 0.81 | ADRB2 (0.61) | ADRB2ADRB1ADRB3SLC2A1ADRA1A | |
| Salmefamol SCHEMBL18458 | 0.81 | ADRB2 (0.67) | ADRB2ADRB1ADRB3SLC2A1ADRA1A | |
| Salmefamol SCHEMBL20285629 | 0.81 | ADRB2 (0.67) | ADRB2ADRB1ADRB3SLC2A1ADRA1A | |
| Salmefamol SCHEMBL30361710 | 0.81 | ADRB2 (0.67) | ADRB2ADRB1ADRB3SLC2A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023385-A1 | Ethanamine derivatives, their preparation and use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-02-04 | — | — | EP | disclosed |