SCHEMBL11245853

SCHEMBL11245853

O=S(=O)(O)Oc1ccc(Cl)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.61
CA9 Q16790 4/20 0.61
CA1 P00915 3/20 0.61
TDP1 Q9NUW8 1/20 0.59
CA12 O43570 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
PPARG P37231 1/20 0.46
ENPP1 P22413 5/20 0.44
ENPP3 O14638 4/20 0.44
NFE2L2 Q16236 1/20 0.43
ALDH1A1 P00352 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
ENPP2 Q13822 3/20 0.42
HPGD P15428 1/20 0.41
APEX1 P27695 1/20 0.40
CA3 P07451 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrazine SCHEMBL28050535 0.96 CA2 (0.63) CA2CA9CA1TDP1CA12
SCHEMBL7910581 0.87 GLA (0.53) CA2CA9CA1TDP1GLA
Ammonia Solution, Strong SCHEMBL2908474 0.85 GLA (0.52) CA2CA9CA1TDP1GLA
SCHEMBL29105126 0.82 CA2 (0.57) CA2CA9CA1TDP1CA12
SCHEMBL28378514 0.80 CA2 (0.67) CA2CA9CA1TDP1CA12
Chlorfenson SCHEMBL116752 0.79 TDP1 (0.81) CA2CA9CA1TDP1CA12
Chlorfenson SCHEMBL7194888 0.79 TDP1 (0.81) CA2CA9CA1TDP1CA12
SCHEMBL31634373 0.78 CA2 (0.64) CA2CA9CA1TDP1CA12
Cyclohexane SCHEMBL8339037 0.78 GLA (0.47) CA2CA9CA1GLAGAA
SCHEMBL4348245 0.78 CA2 (0.64) CA2CA9CA1TDP1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117736125-A Process for synthesizing 4-substituted thiophenol 大连双硼医药化工有限公司 2024-03-22 CN disclosed
US-7442485-B2 Lithographic process involving on press development FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
EP-1484177-B1 Lithographic process involving on press development FUJIFILM CORP (JP) 2007-08-29 EP disclosed
US-4318783-A Process for the preparation of optionally substituted benzaldehyde dialkyl acetals BAYER AKTIENGESELLSCHAFT (DE) 1982-03-09 US disclosed