SCHEMBL4348245

SCHEMBL4348245

O=S(=O)(Cl)Oc1ccc(Cl)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 4/20 0.64
CA9 Q16790 4/20 0.64
CA1 P00915 3/20 0.64
TDP1 Q9NUW8 1/20 0.55
PPARG P37231 1/20 0.47
CA12 O43570 2/20 0.46
NFE2L2 Q16236 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
CA3 P07451 1/20 0.41
CA4 P22748 1/20 0.41
CA6 P23280 1/20 0.41
CA5A P35218 1/20 0.41
CA7 P43166 1/20 0.41
CA13 Q8N1Q1 1/20 0.41
CA14 Q9ULX7 1/20 0.41
CA5B Q9Y2D0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28378514 0.82 CA2 (0.67) CA2CA9CA1TDP1PPARG
SCHEMBL29133406 0.81 CA2 (0.59) CA2CA9CA1TDP1PPARG
SCHEMBL9529411 0.80 SOS1 (0.47) CA2CA9CA1CA12CA7
SCHEMBL31634373 0.80 CA2 (0.64) CA2CA9CA1TDP1PPARG
SCHEMBL197150 0.78 CA2 (0.61) CA2CA9CA1TDP1PPARG
SCHEMBL2236572 0.78 CA2 (1.00) CA2CA9CA1TDP1CA12
SCHEMBL1941544 0.78 CA2 (0.61) CA2CA9CA1TDP1PPARG
SCHEMBL11668250 0.78 CA2 (0.61) CA2CA9CA1TDP1PPARG
SCHEMBL11245853 0.78 CA2 (0.61) CA2CA9CA1TDP1PPARG
SCHEMBL4822537 0.78 CA1 (0.61) CA2CA9CA1PPARGCA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1115340-C Process for synthesizing acetylsulfanilic acid and its salts LIU JICAI (CN) 2003-07-23 CN claimed
CN-1257865-A Process for synthesizing acetylsulfanilic acid and its salts LIU JICAI (CN) 2000-06-28 CN claimed
US-4902730-A Fibre reinforced polyphenylene sulphide BAYER AKTIENGESELLSCHAFT (DE) 1990-02-20 US claimed
US-4880576-A HALOGENATION OF ACIDS, FORMAMIDE CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 US claimed
EP-4702010-A1 PHOTOACTIVE COMPOUNDS Merck Patent GmbH (DE) 2026-03-04 EP disclosed
WO-2024223739-A1 PHOTOACTIVE COMPOUNDS MERCK PATENT GMBH (DE) 2024-10-31 WO disclosed
US-9580386-B2 Substituted 4-aminocyclohexane derivatives GRÜNENTHAL (DE) 2017-02-28 US disclosed
US-9403767-B2 Substituted 4-aminocyclohexane derivatives GRUENENTHAL GMBH (DE) 2016-08-02 US disclosed
US-20140357634-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES Grünenthal GmbH (DE) 2014-12-04 US disclosed
US-8835689-B2 Substituted 4-aminocyclohexane derivatives Grünenthal GmbH (DE) 2014-09-16 US disclosed
US-20130197095-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES Grünenthal GmbH (DE) 2013-08-01 US disclosed
US-20120202810-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES GRUNENTHAL GMBH (DE) 2012-08-09 US disclosed
US-4902730-A Fibre reinforced polyphenylene sulphide BAYER AKTIENGESELLSCHAFT (DE) 1990-02-20 US disclosed
US-4880576-A HALOGENATION OF ACIDS, FORMAMIDE CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 1989-11-14 US disclosed
US-4565648-A FOR PRODUCTION OF POLYURETHANES BAYER AKTIENGESELLSCHAFT (DE) 1986-01-21 US disclosed
US-4388246-A THERMAL SPLITTING OF CARBAMATES BAYER AKTIENGESELLSCHAFT (DE) 1983-06-14 US disclosed
EP-0026040-A1 Substituted benzophenone hydrazones, pesticidal compositions containing them and method of combating pests FBC LIMITED (GB) 1981-04-01 EP disclosed
EP-0010249-A2 Herbicidal agents, process for their preparation and their use in combating weeds BAYER AG (DE) 1980-04-30 EP disclosed
EP-0010250-A2 Use of Sulfonanilides in inhibition of plant growth BAYER AG (DE) 1980-04-30 EP disclosed
US-4006186-A MULTISTAGE FROM A PHENYLSULFONYL CHLORIDE AND HYDRAZINE BAYER AKTIENGESELLSCHAFT (DT) 1977-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140357634-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES OPRL1, OPRK1, OPRD1 CA2 2018/4885CA9 4645/4885CA1 2538/4885
US-20120202810-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES OPRL1, OPRK1, OPRD1 CA2 2018/4885CA9 4645/4885CA1 2538/4885
US-20130197095-A1 SUBSTITUTED 4-AMINOCYCLOHEXANE DERIVATIVES OPRL1, OPRK1, OPRD1 CA2 2018/4885CA9 4645/4885CA1 2538/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.