Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.49 |
| ▸ | GALR3 | O60755 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250575 | 0.92 | SMN1; SMN2 (0.59) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11244741 | 0.82 | LDHA (0.59) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11250162 | 0.81 | HTT (0.62) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11249235 | 0.80 | APP (0.56) | SMN1; SMN2MAPK1APPKMT2AMEN1 | |
| SCHEMBL11262586 | 0.79 | LDHA (0.55) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11261445 | 0.78 | SMN1; SMN2 (0.63) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11249774 | 0.77 | SMN1; SMN2 (0.66) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11251147 | 0.76 | LDHA (0.56) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL11254596 | 0.76 | HTT (0.66) | LDHASMN1; SMN2LMNAGAAALPG | |
| SCHEMBL12199178 | 0.75 | SMN1; SMN2 (0.77) | LDHASMN1; SMN2LMNAGAAALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |