Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | LDHA | P00338 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 4/20 | 0.68 |
| ▸ | ALPG | P10696 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 6/20 | 0.67 |
| ▸ | EGFR | P00533 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.67 |
| ▸ | APP | P05067 | 3/20 | 0.67 |
| ▸ | CCNC | P24863 | 1/20 | 0.65 |
| ▸ | CDK8 | P49336 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.61 |
| ▸ | GALR3 | O60755 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL170193 | 0.89 | LMNA (0.97) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL31197370 | 0.87 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL15922842 | 0.87 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| Hydrochloric Acid SCHEMBL8522254 | 0.87 | SMN1; SMN2 (0.94) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL15923566 | 0.87 | LMNA (1.00) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL10061697 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL11249774 | 0.85 | SMN1; SMN2 (0.66) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL11261445 | 0.83 | SMN1; SMN2 (0.63) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL11244483 | 0.83 | LDHA (0.74) | SMN1; SMN2LMNAS1PR2NPSR1LDHA | |
| SCHEMBL29898477 | 0.83 | LMNA (0.75) | SMN1; SMN2LMNAS1PR2NPSR1LDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2903978-B1 | GDF-8 INHIBITORS | RIGEL PHARMACEUTICALS INC (US) | 2022-12-07 | — | — | EP | claimed |
| US-8969577-B2 | Curable composition comprising a thermolatent base | BASF SE (DE) | 2015-03-03 | — | — | US | disclosed |
| WO-2014123900-A1 | ANTI-CANCER AND ANTI-HIV COMPOUNDS | SIRENAS MARINE DISCOVERY (US) | 2014-08-14 | — | — | WO | disclosed |
| US-20110245375-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | BASF SE (DE) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245375-A1 | CURABLE COMPOSITION COMPRISING A THERMOLATENT BASE | COIL, MAPT, ASH2L | SMN1; SMN2 1451/4885LMNA 1354/4885S1PR2 4507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.