Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | QPCT | Q16769 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259667 | 0.95 | LMNA (0.46) | LMNAQPCTKDM4EHTTCYP19A1 | |
| SCHEMBL11245761 | 0.88 | LMNA (0.43) | LMNAQPCTKDM4EHTTCYP19A1 | |
| SCHEMBL11238443 | 0.87 | QPCT (0.49) | QPCTKDM4EHTTCYP19A1TSHR | |
| SCHEMBL11229752 | 0.87 | QPCT (0.50) | QPCTKDM4ECYP19A1TSHR | |
| SCHEMBL11247642 | 0.84 | CYP19A1 (0.47) | CYP19A1TBXAS1 | |
| SCHEMBL11236630 | 0.84 | MEN1 (0.54) | LMNAQPCTKDM4EHTTTSHR | |
| SCHEMBL11242197 | 0.84 | QPCT (0.49) | QPCTKDM4ECYP19A1TSHRTBXAS1 | |
| SCHEMBL11246832 | 0.84 | QPCT (0.48) | QPCTHTTCYP19A1TSHRPRKCI | |
| SCHEMBL11230325 | 0.83 | LMNA (0.45) | LMNAQPCTKDM4EHTTCYP19A1 | |
| SCHEMBL11236394 | 0.83 | HMOX1 (0.45) | LMNAQPCTKDM4EHTTCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |