Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | SCD | O00767 | 3/20 | 0.52 |
| ▸ | MMP13 | P45452 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11239574 | 0.88 | KMT2A (0.54) | MAPTNPC1MMP13RAB9ASMN1; SMN2 | |
| SCHEMBL11236457 | 0.86 | KMT2A (0.57) | MAPTNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11220429 | 0.81 | ADORA3 (0.62) | MAPTNPC1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL18094458 | 0.74 | ADORA3 (0.69) | MAPTNPC1LMNAKDM4ESCD | |
| SCHEMBL11249270 | 0.72 | NPC1 (0.53) | MAPTNPC1KDM4ESCDRAB9A | |
| SCHEMBL4293155 | 0.70 | STAT3 (0.64) | MAPTNPC1LMNAKDM4ESCD | |
| SCHEMBL3191246 | 0.69 | NPC1 (1.00) | MAPTNPC1LMNAKDM4ESCD | |
| SCHEMBL11240993 | 0.69 | THRB (0.58) | MAPTNPC1LMNAKDM4ERAB9A | |
| SCHEMBL11051554 | 0.69 | CA1 (0.65) | MAPTNPC1LMNAKDM4ESCD | |
| SCHEMBL2179411 | 0.69 | NPC1 (0.69) | MAPTNPC1LMNAKDM4ESCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4343945-A | 5-Benzamido-3-trichloromethyl-1,2,4-thiadiazoles and their use as herbicides, fungicides and insecticides | OLIN CORPORATION (US) | 1982-08-10 | — | — | US | disclosed |