Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.39 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11246260 | 1.00 | PARP10 (0.52) | PARP10SMN1; SMN2CYP2C19OPRK1KCNH2 | |
| SCHEMBL11247678 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11247680 | 0.90 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11243022 | 0.86 | MMP9 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11243025 | 0.86 | MMP9 (0.50) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11233159 | 0.81 | POLB (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11233168 | 0.81 | POLB (0.48) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 | |
| SCHEMBL11243294 | 0.81 | F2RL3 (0.48) | SMN1; SMN2CYP2C19OPRK1KCNH2NPC1 | |
| SCHEMBL11243290 | 0.81 | F2RL3 (0.48) | SMN1; SMN2CYP2C19OPRK1KCNH2NPC1 | |
| SCHEMBL6954138 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2CYP2C19NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4320137-A | Derivatives of perhydro-aza-heterocycles | CIBA-GEIGY CORPORATION (US) | 1982-03-16 | — | — | US | disclosed |
| US-4246269-A | Antidepressant piperidinones | CIBA-GEIGY CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4160837-A | ANTIDEPRESSANTS | CIBA-GEIGY CORPORATION (US) | 1979-07-10 | — | — | US | disclosed |