Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.55 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.51 |
| ▸ | QPCT | Q16769 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11243829 | 0.92 | CYP19A1 (0.54) | CYP19A1CYP11B1CYP11B2TBXAS1QPCT | |
| SCHEMBL11259784 | 0.89 | TBXAS1 (0.55) | TBXAS1EGLN3QPCTALDH1A1 | |
| SCHEMBL11253750 | 0.87 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11242023 | 0.86 | KMT2A (0.53) | TBXAS1EGLN3TDP1L3MBTL1 | |
| SCHEMBL11260419 | 0.86 | TBXAS1 (0.59) | TBXAS1EGLN3 | |
| SCHEMBL11244197 | 0.86 | CYP11B1 (0.56) | CYP11B1CYP11B2TBXAS1EGLN3ALDH1A1 | |
| SCHEMBL11251579 | 0.86 | CYP2A6 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11233236 | 0.86 | HMOX1 (0.57) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11231149 | 0.85 | EGLN3 (0.58) | CYP19A1CYP11B1CYP11B2TBXAS1EGLN3 | |
| SCHEMBL11248355 | 0.85 | CYP19A1 (0.59) | CYP19A1CYP11B1CYP11B2TBXAS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4359475-A | SPERMICIDES, MICROBIOCIDES OR ANTICONVULSANTS | SYNTEX (U.S.A.) INC. (US) | 1982-11-16 | — | — | US | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |