SCHEMBL11246374

SCHEMBL11246374

Clc1cc(Cl)c(SCCN2CCCC2)cc1Cl

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.45
SIGMAR1 Q99720 8/20 0.44
CYP1A2 P05177 3/20 0.42
CYP2D6 P10635 3/20 0.42
TMEM97 Q5BJF2 1/20 0.42
LTA4H P09960 1/20 0.41
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TSHR P16473 3/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 3/20 0.38
TP53 P04637 2/20 0.37
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
CYP3A4 P08684 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11345755 0.67 LTA4H (0.50) ALOX15SIGMAR1LTA4HSMN1; SMN2GRIN2B
SCHEMBL1928225 0.67 LTA4H (0.50) ALOX15SIGMAR1LTA4HSMN1; SMN2ALDH1A1
SCHEMBL11345105 0.67 HRH3 (0.53) ALOX15SIGMAR1CYP2D6LTA4HSMN1; SMN2
SCHEMBL1927719 0.66 KDM4E (0.49) ALOX15SIGMAR1LTA4HSMN1; SMN2ALDH1A1
SCHEMBL19273423 0.64 LTA4H (0.75) SIGMAR1LTA4HSMN1; SMN2ALDH1A1NPC1
SCHEMBL8915575 0.64 ALOX15 (0.38) ALOX15TMEM97LTA4HPOLBSMN1; SMN2
SCHEMBL11624401 0.64 ALOX15 (0.44) ALOX15CYP1A2TMEM97LTA4HPOLB
SCHEMBL11622814 0.64 ALOX15 (0.44) ALOX15CYP1A2TMEM97LTA4HPOLB
SCHEMBL11536449 0.63 LTA4H (0.73) SIGMAR1LTA4HSMN1; SMN2ALDH1A1NPC1
SCHEMBL4265997 0.62 LTA4H (0.61) SIGMAR1LTA4HSMN1; SMN2ALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0017209-B1 SUBSTITUTED ALKYLAMMONIUM SALTS, THEIR PREPARATION AND USE IN PLANT GROWTH REGULATION BASF Aktiengesellschaft (DE) 1982-12-22 EP disclosed
US-4350518-A Plant growth regulating substituted alkylammonium salts BASF AKTIENGESELLSCHAFT (DE) 1982-09-21 US disclosed