Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | QPCT | Q16769 | 3/20 | 0.45 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11237009 | 0.94 | MEN1 (0.50) | MEN1KMT2AATMQPCTHMOX1 | |
| SCHEMBL11238847 | 0.93 | MEN1 (0.49) | MEN1KMT2AATMQPCTHMOX1 | |
| SCHEMBL11236215 | 0.89 | HMOX1 (0.42) | KMT2AHMOX1ALDH1A1KDM4ECYP1A2 | |
| SCHEMBL11245162 | 0.88 | HMOX1 (0.47) | KMT2AQPCTHMOX1ALDH1A1KDM4E | |
| SCHEMBL11243032 | 0.88 | HMOX1 (0.57) | HMOX1KDM4ETSHR | |
| SCHEMBL11235557 | 0.86 | HMOX1 (0.47) | HMOX1 | |
| SCHEMBL10852213 | 0.86 | HMOX1 (0.46) | MEN1KMT2AATMQPCTHMOX1 | |
| SCHEMBL11243811 | 0.85 | MEN1 (0.51) | MEN1KMT2AATMQPCTALDH1A1 | |
| SCHEMBL11233835 | 0.85 | KMT2A (0.45) | MEN1KMT2AHMOX1ALDH1A1KDM4E | |
| SCHEMBL11237122 | 0.84 | MEN1 (0.52) | MEN1KMT2AATMQPCTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |