Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253014 | 0.93 | HMOX1 (0.46) | HMOX1TBXAS1CYP19A1 | |
| SCHEMBL11242355 | 0.92 | HMOX1 (0.45) | HMOX1TBXAS1CYP19A1 | |
| SCHEMBL11243032 | 0.89 | HMOX1 (0.57) | HMOX1 | |
| SCHEMBL11245162 | 0.89 | HMOX1 (0.47) | HMOX1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11257861 | 0.87 | HMOX1 (0.43) | HMOX1TBXAS1CYP19A1 | |
| SCHEMBL11233835 | 0.86 | KMT2A (0.45) | HMOX1CYP11B1CYP11B2 | |
| SCHEMBL11246401 | 0.86 | MEN1 (0.46) | HMOX1 | |
| SCHEMBL11236215 | 0.84 | HMOX1 (0.42) | HMOX1TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL11243518 | 0.84 | TBXAS1 (0.47) | TBXAS1CYP19A1CYP11B1CYP11B2OPRM1 | |
| SCHEMBL11235683 | 0.83 | HMOX1 (0.55) | HMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |