Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11242956 | 0.86 | HMOX1 (0.70) | HMOX1 | |
| SCHEMBL11243076 | 0.86 | HMOX1 (0.76) | HMOX1 | |
| SCHEMBL11245098 | 0.84 | CYP2C9 (0.44) | HMOX1LMNAADRA1A | |
| SCHEMBL11240321 | 0.83 | HMOX1 (0.52) | HMOX1TSHR | |
| SCHEMBL11252422 | 0.82 | HMOX1 (0.41) | HMOX1USP2ALDH1A1LMNAALOX15 | |
| SCHEMBL11241392 | 0.82 | CYP2C9 (0.43) | HMOX1LMNAADRA1A | |
| SCHEMBL11249464 | 0.81 | HMOX1 (0.82) | HMOX1 | |
| SCHEMBL11239858 | 0.81 | HMOX1 (0.40) | HMOX1USP2ALDH1A1LMNAALOX15 | |
| SCHEMBL11242305 | 0.81 | HMOX1 (0.67) | HMOX1 | |
| SCHEMBL11236268 | 0.80 | KCNH2 (0.40) | HMOX1USP2ALDH1A1LMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049565-A2 | Derivatives of substituted N-alkylimidazoles, their preparation and pharmaceutical compositions containing them | SYNTEX (U.S.A.) INC. (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4321272-A | Derivatives of substituted N-alkylimidazoles | SYNTEX (U.S.A.) INC. (US) | 1982-03-23 | — | — | US | disclosed |