⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11250808 | 0.87 | LMNA (0.32) | — | |
| SCHEMBL379715 | 0.80 | LMNA (0.32) | — | |
| SCHEMBL11246051 | 0.76 | — | — | |
| SCHEMBL329584 | 0.75 | LMNA (0.30) | — | |
| SCHEMBL380123 | 0.75 | LMNA (0.30) | — | |
| SCHEMBL12549891 | 0.73 | — | — | |
| SCHEMBL7767333 | 0.73 | — | — | |
| SCHEMBL17882508 | 0.71 | LMNA (0.36) | — | |
| SCHEMBL2720576 | 0.69 | LMNA (0.32) | — | |
| SCHEMBL3922908 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292234-A | TRIALKOXYSILYL-AZIDES, -THIOSULFENAMIDES, SILACYCLOALKYL-MERCAPTANS, AND/OR -DISULFIDES; COUPLING | PHILLIPS PETROLEUM CO. (US) | 1981-09-29 | — | — | US | claimed |
| EP-0018503-A2 | Silyl azides, their use for producing silica reinforced rubber, and silica reinforced rubber | PHILLIPS PETROLEUM COMPANY (US) | 1980-11-12 | — | — | EP | claimed |
| US-4359342-A | Silica reinforced rubber | PHILLIPS PETROLEUM COMPANY (US) | 1982-11-16 | — | — | US | disclosed |
| US-4292234-A | TRIALKOXYSILYL-AZIDES, -THIOSULFENAMIDES, SILACYCLOALKYL-MERCAPTANS, AND/OR -DISULFIDES; COUPLING | PHILLIPS PETROLEUM CO. (US) | 1981-09-29 | — | — | US | disclosed |
| EP-0018503-A2 | Silyl azides, their use for producing silica reinforced rubber, and silica reinforced rubber | PHILLIPS PETROLEUM COMPANY (US) | 1980-11-12 | — | — | EP | disclosed |