SCHEMBL11250808

SCHEMBL11250808

CO[Si](CCCSSN(C)C)(OC)OC

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11246509 0.87
SCHEMBL79932 0.82 LMNA (0.39) LMNA
SCHEMBL10707740 0.80 MGLL (0.37) LMNA
SCHEMBL3851335 0.79 LMNA (0.30) LMNA
SCHEMBL80639 0.78 LMNA (0.36) LMNA
SCHEMBL380401 0.78 LMNA (0.36) LMNA
SCHEMBL17882508 0.78 LMNA (0.36) LMNA
SCHEMBL692679 0.76 LMNA (0.35) LMNA
SCHEMBL5691236 0.76 LMNA (0.35) LMNA
SCHEMBL5072211 0.76 LMNA (0.35) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4292234-A TRIALKOXYSILYL-AZIDES, -THIOSULFENAMIDES, SILACYCLOALKYL-MERCAPTANS, AND/OR -DISULFIDES; COUPLING PHILLIPS PETROLEUM CO. (US) 1981-09-29 US claimed
EP-0018503-A2 Silyl azides, their use for producing silica reinforced rubber, and silica reinforced rubber PHILLIPS PETROLEUM COMPANY (US) 1980-11-12 EP claimed
US-4359342-A Silica reinforced rubber PHILLIPS PETROLEUM COMPANY (US) 1982-11-16 US disclosed
US-4292234-A TRIALKOXYSILYL-AZIDES, -THIOSULFENAMIDES, SILACYCLOALKYL-MERCAPTANS, AND/OR -DISULFIDES; COUPLING PHILLIPS PETROLEUM CO. (US) 1981-09-29 US disclosed
EP-0018503-A2 Silyl azides, their use for producing silica reinforced rubber, and silica reinforced rubber PHILLIPS PETROLEUM COMPANY (US) 1980-11-12 EP disclosed