Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 10/20 | 0.68 |
| ▸ | PDE5A | O76074 | 3/20 | 0.63 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | ACHE | P22303 | 4/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244411 | 0.85 | APP (0.62) | APPPDE5ABCHEACHERAD52 | |
| SCHEMBL17799869 | 0.81 | APP (1.00) | APPPDE5ABCHEACHELMNA | |
| SCHEMBL11264589 | 0.81 | APP (0.63) | APPPDE5ABCHEACHERAD52 | |
| SCHEMBL11246231 | 0.80 | HTT (0.68) | APPLMNAKDM4EMAPTKMT2A | |
| SCHEMBL3113122 | 0.78 | APP (1.00) | APPPDE5ABCHEACHERAD52 | |
| SCHEMBL29388255 | 0.78 | APP (1.00) | APPPDE5ABCHEACHERAD52 | |
| SCHEMBL10839105 | 0.77 | APP (0.70) | APPPDE5ARAD52MAPTKMT2A | |
| SCHEMBL4904310 | 0.77 | APP (0.70) | APPPDE5ABCHEACHEKDM4E | |
| SCHEMBL30125140 | 0.77 | APP (0.70) | APPPDE5ARAD52MAPTKMT2A | |
| SCHEMBL7337304 | 0.77 | APP (0.70) | APPPDE5ARAD52LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4323680-A | 4-Aminoquinazoline compounds useful as agricultural fungicides | SANKYO COMPANY LIMITED (JP) | 1982-04-06 | — | — | US | disclosed |
| US-4213987-A | 4-AMINOQUINAZOLINES | SANKYO COMPANY LIMITED (JP) | 1980-07-22 | — | — | US | disclosed |