SCHEMBL11246792

SCHEMBL11246792

CCCCCC(C)(C)c1cc(-n2nc3ccccc3n2)cc(C(C)(C)c2ccccc2O)c1

nearest known ligand 0.40

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 18/20 0.40
CNR2 P34972 16/20 0.40
GPR18 Q14330 3/20 0.38
GPR55 Q9Y2T6 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567729 0.84 PPARG (0.36)
SCHEMBL8861276 0.84 PTGS2 (0.35)
SCHEMBL3680277 0.81 PPARG (0.41) CNR1CNR2
SCHEMBL7575684 0.81 CNR2 (0.44) CNR1CNR2
SCHEMBL29351747 0.81 PPARG (0.41) CNR1CNR2
SCHEMBL11470802 0.80 CNR1 (0.35) CNR1CNR2
SCHEMBL10359109 0.79 NPC1 (0.43) CNR1CNR2
SCHEMBL224924 0.76 CNR1 (0.38) CNR1CNR2GPR18GPR55
SCHEMBL673359 0.75 CNR1 (0.40) CNR1CNR2GPR18GPR55
SCHEMBL123853 0.75 NPC1 (0.51) CNR1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4347180-A High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes CIBA-GEIGY CORPORATION (US) 1982-08-31 US disclosed
US-4275004-A High caustic coupling process for preparing substituted 2-nitro-2'-hydroxyazobenzenes CIBA-GEIGY CORPORATION (US) 1981-06-23 US disclosed