SCHEMBL7575684

SCHEMBL7575684

CCCCCC(C)(C)c1cc(-c2cc(-n3nc4ccccc4n3)cc(C(C)(C)CCCCC)c2)cc(-n2nc3ccccc3n2)c1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 17/20 0.44
CNR1 P21554 15/20 0.39
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11246792 0.81 CNR1 (0.40) CNR2CNR1
SCHEMBL20404520 0.77 KDM4E (0.46) KDM4EHPGDPPARGPPARA
SCHEMBL7588136 0.76 CNR1 (0.44) CNR2CNR1
SCHEMBL2464792 0.76 CNR2 (0.44) CNR2CNR1KDM4E
SCHEMBL2467398 0.75 CNR2 (0.46) CNR2CNR1
SCHEMBL673359 0.75 CNR1 (0.40) CNR2CNR1
SCHEMBL19376327 0.75 CNR2 (0.38) CNR2CNR1
SCHEMBL3887357 0.74 CNR1 (0.53) CNR2CNR1
SCHEMBL123853 0.74 NPC1 (0.51) CNR2CNR1
SCHEMBL22289027 0.74 CNR1 (0.42) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238003-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2002-09-11 EP disclosed
WO-2001034694-A1 MONO- AND BIS- BENZOTRIAZOLYLDIHYDROXYBIARYL UV ABSORBERS CYTEC TECHNOLOGY CORP. (US) 2001-05-17 WO disclosed