Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | DHFR | P00374 | 2/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11255371 | 0.87 | POLB (0.56) | KMT2APOLBMAPTMEN1MAPK1 | |
| SCHEMBL11245609 | 0.80 | ALDH1A1 (0.48) | KMT2ALMNAALDH1A1NPSR1FAAH | |
| SCHEMBL4161662 | 0.80 | MEN1 (0.54) | KMT2AMEN1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11252096 | 0.79 | MAPT (0.55) | KMT2APOLBGSRMAPTMEN1 | |
| SCHEMBL11242309 | 0.79 | SLC2A2 (0.51) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL11240983 | 0.75 | KMT2A (0.52) | KMT2AMAPTMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL11731366 | 0.74 | HPGD (0.54) | KMT2AMAPTMEN1MAPK1LMNA | |
| SCHEMBL6123566 | 0.74 | ALDH1A1 (0.61) | MAPTCA1CA2SMN1; SMN2ALDH1A1 | |
| SCHEMBL11249311 | 0.74 | RPA1 (0.51) | KMT2APOLBMAPTMEN1CA1 | |
| SCHEMBL1997120 | 0.72 | ALDH1A1 (0.53) | KMT2AMEN1MAPK1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325962-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIDYRETICS | BYK-GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-04-20 | — | — | US | disclosed |
| US-4146721-A | ANALGESICS, ANTIINFLAMMATORY AGENTS AND ANTIPYRETICS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1979-03-27 | — | — | US | disclosed |