Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763595 | 0.94 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1L3MBTL1PTPN11MCL1 | |
| SCHEMBL9446930 | 0.87 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1MAP4K4KDM4EGAA | |
| SCHEMBL29109658 | 0.85 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1PTPN11MCL1 | |
| SCHEMBL18763585 | 0.82 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1PTPN11MCL1 | |
| SCHEMBL12096703 | 0.82 | PTPN11 (0.47) | SMN1; SMN2ALDH1A1PTPN11MCL1MAP4K4 | |
| SCHEMBL7591657 | 0.81 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1KDM4EGAARXFP1 | |
| SCHEMBL18763587 | 0.79 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1PTPN11PRKAB2PRKAG1 | |
| SCHEMBL9186976 | 0.78 | MCL1 (0.44) | ALDH1A1L3MBTL1MCL1PRKAB2PRKAG1 | |
| SCHEMBL11517805 | 0.78 | PTPN11 (0.65) | SMN1; SMN2ALDH1A1PTPN11MCL1KDM4E | |
| SCHEMBL8962717 | 0.78 | RARB (0.53) | SMN1; SMN2ALDH1A1PTPN11MCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4358391-A | BRANCHED POLYSILOXANES | WACKER-CHEMIE GMBH (DE) | 1982-11-09 | — | — | US | disclosed |