SCHEMBL18763585

SCHEMBL18763585

C=CCCCOc1ccc(C(=O)O)c(-c2ccc(-c3ccccc3)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HDAC1 Q13547 4/20 0.48
HDAC2 Q92769 4/20 0.48
HDAC8 Q9BY41 6/20 0.46
PTPN11 Q06124 4/20 0.45
HDAC3 O15379 3/20 0.44
HDAC4 P56524 3/20 0.44
HDAC7 Q8WUI4 3/20 0.44
HDAC10 Q969S8 3/20 0.44
HDAC11 Q96DB2 3/20 0.44
HDAC6 Q9UBN7 3/20 0.44
HDAC9 Q9UKV0 3/20 0.44
HDAC5 Q9UQL6 3/20 0.44
ALDH2 P05091 1/20 0.43
MAOA P21397 1/20 0.43
MAOB P27338 1/20 0.43
MCL1 Q07820 1/20 0.42
PPARG P37231 1/20 0.42
PPARD Q03181 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29109658 0.90 ALDH1A1 (0.52) ALDH1A1L3MBTL1HDAC1HDAC2HDAC8
SCHEMBL18763595 0.89 ALDH1A1 (0.52) ALDH1A1L3MBTL1HDAC8PTPN11ALDH2
SCHEMBL8913753 0.87 ALDH1A1 (0.51) ALDH1A1L3MBTL1HDAC1HDAC2PTPN11
Hydrochloric Acid SCHEMBL9177131 0.86 ALDH1A1 (0.55) ALDH1A1L3MBTL1HDAC1HDAC2HDAC8
SCHEMBL18763587 0.86 ALDH1A1 (0.52) ALDH1A1L3MBTL1HDAC1HDAC2PTPN11
SCHEMBL5095993 0.86 GAA (0.47) ALDH1A1PTPN11ALDH2MAOAMAOB
SCHEMBL18763591 0.85 ALDH1A1 (0.48) ALDH1A1L3MBTL1PTPN11ALDH2MAOA
SCHEMBL8850740 0.83 GAA (0.49) ALDH1A1PTPN11ALDH2MAOAMAOB
SCHEMBL11247571 0.82 SMN1; SMN2 (0.51) ALDH1A1L3MBTL1PTPN11MCL1
SCHEMBL8604099 0.82 PTPN11 (0.59) ALDH1A1L3MBTL1HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170115075-A1 HEAT-TRANSMITTING MODIFIER FOR ELASTOMER, HEAT-TRANSMISSION-MODIFIED CRYSTALLINE ELASTOMER, METHOD FOR USING CRYSTALLINE POLYMER AND PRECURSOR THEREOF, METHOD FOR HEAT-TRANSMISSION MODIFICATION OF ELASTOMER, HEATER BODY, AND HEATED BODY I.S.T CORPORATION (JP) 2017-04-27 US claimed